Sunday, December 17, 2017

Antibody Treatment For Myasthenia Gravis From Argenx Proves Effective

A Phase II proof of concept study has shown that one of Argenx’ antibodies is effective in treating the neuromuscular disease myasthenia gravis.

Argenx has released the results from a Phase II trial with ARGX-113 (efgartigimod), in which the antibody therapy has proved to provide a significant improvement in patients with generalized myasthenia gravis, a form of the disease that affects the strength of multiple muscles simultaneously. Argenx’ stock on Euronext Brussels is up by 24% a few hours after it opened this

Thursday, November 16, 2017

Myasthenia Gravis Symptoms Could Be Relieved By Cognitive Behavioral Therapy

Cognitive Behavioral Therapy (CBT) should be considered as a first-line treatment for myasthenia gravis (MG) patients who also suffer from anxiety, depression, or insomnia disorders, a new study urges.

The study, “Cognitive-Behavioral Therapy for Psychiatric Comorbidity in a Case of Muscle-Specific Kinase–Positive Myasthenia Gravis,” appeared in the journal The Primary Care Companion for CNS Disorders.

MG patients frequently have depression and anxiety. Medications usually help, though some patients suffer adverse events. CBT, a type of psychotherapy, can

Tuesday, November 14, 2017

Relatives Of Myasthenia Gravis Patients Have Higher Risk Of Developing The Disease

Researchers in Taiwan have found that first-degree relatives of individuals with myasthenia gravis have a higher risk of developing the disease. The risk is greater for patients’ siblings, the study found.

The study, “Familial aggregation of myasthenia gravis in affected families: a population-based study,” appeared in the journal Clinical Epidemiology.

Wednesday, October 18, 2017

MG Respiratory Failure Requires Specific Treatments in the ER, Review Contends

Myasthenic crisis is a common complication in patients with myasthenia gravis (MG), marked by exacerbation of MG symptoms and respiratory failure. But with the rarity of MG, and its similarity to a range of other neuromuscular diseases, proper detection and treatment might fail, researchers argue.

Wednesday, September 27, 2017

It Wasn't A Stroke But All The Signs Pointed That Way

“Mom?” the middle-aged man asked. He recognized the voice, but the words were muffled and strange. I’ll be right over, he said into the phone. The 15-minute drive from his small Connecticut town to his mother’s seemed to last forever. Had she had a stroke? She was 94, and though she’d always been

Friday, September 8, 2017

Vitamin D3 Deficiency Linked To Myasthenia Gravis - Study Confirms

Vitamin D From Fish Oil 

Myasthenia gravis (MG) is a chronic autoimmune neuromuscular disorder. Vitamin D has important roles both in the autoimmune response and in skeletal muscles. We determined the levels of 25-hydroxy vitamin D [25(OH)D] in patients with MG and in healthy subjects to determine whether vitamin D deficiency is present in MG and whether vitamin D supplementation has beneficial effects on fatigue.

Dentistry and Myasthenia Gravis - What You and Your Dentist Need to Know

Dentistry and Myasthenia Gravis

The following article is courtesy of the Myasthenia Gravis Association of Western Pennsylvania

Dentistry can be a part of normal health care for the myasthenic and should not be feared or avoided. The objective of this article is to give both the dentist and the myasthenic a basis for understanding and communication that will result in

Friday, June 30, 2017

Outcomes After Major Surgery For Patients With Myasthenia Gravis

A couple of months ago I came close to having a total knee replacement but decided against it because of my myasthenia gravis. I just thought it was too risky. My symptoms are pretty much under control and I count myself among those MG patients that have a "relatively normal lifestyle." But I've worked hard to keep it under control and I didn't want to risk a setback. There are plenty of stories on the internet about MG patients having major surgery that worked out well and others that didn't. I just didn't want to take the chance.  

Friday, June 16, 2017

Transfusions, Surgery And Medication: Young Girl With Myasthenia Gravis Is Symptom Free

Ashley Earl-Goulet, pictured with mum Judith, has
 has recovered thanks to more than 600 blood donations
Blood from over 600 people has been used to treat a Timaru teenager with a rare auto-immune disease – and she wants the donors to know the difference it has made.

Ashley Earl-Goulet, 14, is the only child in the South Island and one of just a handful in New Zealand with myasthenia gravis, a long-term neuromuscular disease which weakens muscles – most commonly in the eyes and face.

Ashley's treatment included a blood "product" nick-named "go go juice" by health workers

Wednesday, June 14, 2017

Town Supervisor Steps Down After Fighting Myasthenia Gravis For Two Years

Hornellsville supervisor will leave post at end of year

ARKPORT — Fighting myasthenia gravis for the past two years has been a chore for Ken Isaman. After 28 years as a Hornellsville councilman and supervisor, he will say goodbye to town government at the end of 2017.

The 69-year-old Republican, who also served for 12 years on the Steuben County Legislature, told the Hornellsville Town Board Tuesday night that he will not be a candidate for reelection in the fall. Isaman has been battling health issues

Tuesday, June 13, 2017

Scientists Make First Crystal Model Of Myasthenia Gravis

As a molecular biologist, Kaori Noridomi gets an up-close view of the targets of her investigations. But when she began studying the molecular structures of a rarely diagnosed autoimmune disorder, myasthenia gravis, she decided to step out of the lab for a better view.

Noridomi said she thought she needed to know more than what she saw on a microscope and decided she should meet patients who have myasthenia gravis. She went so far

Sunday, May 14, 2017

Prolonged Asystole (Flat Line) In MG Patient Induced by Pyridostigmine. Successfully Treated with Hyoscyamine

Dr. Mohammad Saud Khan

Reversible acetylcholinesterase inhibitors are used as first-line treatment for myasthenia gravis (MG).

They improve symptoms by increasing concentration of acetylcholine at the neuromuscular junction and stimulating nicotinic receptors. Serious bradyarrhythmias can occur from muscarinic stimulation in heart, which in rare cases may progress to asystole (Flat Lining on ECG monitor).

Friday, April 7, 2017

Together - For Better or Worse

APRIL 06, 2017 12:30 PM
For better, for worse
Senior Living Staff Writer

It has been nearly 15 years since Dwight Harder was diagnosed with Parkinson’s disease — a degenerative disorder of the central nervous system.

With April designated as National Parkinson’s Awareness Month, Dwight hopes his story will be inspirational and, most importantly, educational for people who face chronic illnesses and diseases.

Tuesday, April 4, 2017

MG Walk Welcomed By Mayor Of Brook Run

Mayor Denis Shortal supported the 5th annual Myasthenia Gravis Walk last month at the Brook Run Park in Dunwoody. Mayor Shortal became the first mayor to open a Myasthenia Gravis Walk. The local Myasthenia Gravis chapter was delighted to have support from mayor and look forward to seeing him future events.

Tuesday, February 28, 2017

Positive Outlook Helps Young Woman With Generalized Myasthenia Gravis

Johannesburg – While she calls herself a mother of three “fur-kids”, Megan Hunter’s biggest dream is to have a baby.

“I want to be strong enough to be able to fall pregnant and have a baby. That really is my biggest wish and my heart aches for one.”

The 28-year-old is one in 5 000 people with Myasthenia Gravis: an extremely rare neuromuscular, autoimmune disease that affects all her muscles.

Thursday, February 2, 2017

After Massive Dose of Vitamin D Myasthenia Gravis Patients Goes Into Remission

By Fl├ívio Adsuara Cadegiani  | Published at NCBI  |

Vitamin D has been shown to be related to autoimmune diseases, such as multiple sclerosis and psoriasis. Correlations have been reported between vitamin D levels and prevalence and severity of other autoimmune disorders, and also between vitamin D therapy and disease improvement and remission.

Below is a case report of a patient with severe and refractory myasthenia gravis (MG) who followed a “high-dose vitamin D treatment”, a massive-dose treatment (80 000 to 120 000 IU/day) promoted by a medical center in Brazil (but still not proven), and she had her first complete remission after this type of treatment with increased vitamin D serum levels (400 to 700 ng/mL)